Urobioma, l’eziopatogenesi dei disturbi urinari.

“Nelle donne adulte continentali la composizione del microbioma vescicale differisce in base all’età, con rilevanza per la pratica clinica”

 Per la ricerca sull’urobioma, i metodi di coltura avanzati e/o il sequenziamento del DNA sono le tecniche preferite per il rilevamento dei batteri. L’interpretazione dei test clinici, come l’urinocoltura standard, dovrebbe incorporare la conoscenza che alcune donne hanno urotipi di Gardnerella o Escherichia senza evidenza di alcun disturbo clinico.

Le strategie di cura clinica dovrebbero preservare o ripristinare gli effetti benefici dell’urobioma nativo, poiché l’interruzione di quella comunità microbica potrebbe comportare una vulnerabilità involontaria all’invasione dell’uropatogeno o una crescita eccessiva di patogeni opportunisti. In conclusione dovrebbero essere incoraggiati gli studi longitudinali sulle risposte dell’urobioma alle terapie. Lo speriamo proprio!!

Fonte:

The urobiome of continent adult women: a cross-sectional study

https://obgyn.onlinelibrary.wiley.com/doi/10.1111/1471-0528.15920

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