Glossary, Medical and Scientific Terms
B
- Weak or interrupted urine stream
- Frequent urge to urinate, especially at night (nocturia)
- Sensation of incomplete bladder emptying
- Dribbling after urination
H
Hospital
A hospital is a healthcare facility where doctors, nurses, and specialists treat patients who are sick or injured. It provides emergency care for serious conditions, diagnostic tests like X-rays and blood work, surgery when needed, and rehabilitation to help patients recover. Some hospitals also offer preventive check-ups and physical therapy services.
Hormone
Hormones are chemical messengers produced by glands that travel through the bloodstream to regulate important body functions. They control metabolism, growth, reproduction, mood, sleep, and stress response by telling organs and tissues what to do. For example, testosterone regulates male characteristics and sperm production, while insulin manages blood sugar levels. Hormone imbalances can cause medical conditions treatable with medications or lifestyle changes.
- 95% of infections resolve naturally within 2 years
- Transmission: mainly sexual, but possible via contaminated surfaces
- Prevention: HPV vaccine (Gardasil) protects against major cancer-causing strains
- Screening: Pap smears detect cervical changes early
- Regular check-ups are essential for sexually active patients.
- Scrotum looks enlarged, like a water balloon
- Feeling of heaviness, especially when standing
- Swelling may shrink in the morning, grow during the day
- Primary: No underlying cause (common in babies)
- Secondary: Due to injury, infection, or testicular issues
- Opening on underside of penis (may be near tip, middle, or scrotum)
- Penis may curve downward (chordee)
- Abnormal foreskin (doesn’t cover entire glans)
I
Induratio Penis Plastica (IPP, Peyronie’s Disease)
Peyronie’s disease is a condition where scar tissue forms inside the penis, causing it to curve or bend abnormally, usually during erection. The scar develops in the tunica albuginea, the tough sheath that surrounds the erectile chambers of the penis.
Most men notice a painless or painful lump on the penis shaft, followed by curvature that makes intercourse difficult or impossible. The condition typically develops gradually over weeks or months. Causes include penile injury (often during intercourse), genetics, or connective tissue disorders. Some cases improve naturally over time, but many require treatment. Options include injections directly into the scar tissue, oral medications, or surgery to straighten the penis. Early treatment gives better results and prevents erectile dysfunction.
Iontophoresis
Iontophoresis is a non-invasive treatment method that delivers medication through the skin using a mild electric current, without needles or injections. A small device with electrodes is placed on the skin, and the electric current helps push medication molecules deeper into tissues where they’re needed.
Common uses include treating hyperhidrosis (excessive sweating), pain relief, and anti-inflammatory therapy. The patient feels only a slight tingling sensation during the 15-20 minute session. It’s painless, safe, and ideal for patients who fear needles or have sensitive skin. Multiple sessions are usually needed for best results. The method is particularly useful for localized treatment of small areas like hands, feet, or underarms.
K
Kidney
The kidneys are two bean-shaped organs that filter waste products and excess water from the blood to make urine. They work 24/7 to keep your body healthy by removing toxins and maintaining proper fluid and electrolyte balance.
Each kidney contains about one million tiny filtering units called nephrons. Blood enters the kidney, useful substances like glucose and proteins are reabsorbed, and waste products become urine. The kidneys also produce hormones that regulate blood pressure, red blood cell production, and bone health.
Common kidney problems include infections, stones, chronic disease, and failure. A doctor who specializes in kidney diseases is called a nephrologist. Keeping kidneys healthy requires staying hydrated, managing blood pressure and diabetes, and avoiding excessive salt and NSAIDs. When kidneys fail, dialysis or transplant may be necessary.
L
Laparoscopy (LC, Video-Laparoscopic Surgery – VLC)
Laparoscopy is minimally invasive surgery performed through tiny incisions (usually 3-4 small cuts) instead of one large surgical opening. A thin tube with a camera (laparoscope) is inserted to let the surgeon see inside the abdomen on a monitor while using specialized instruments to perform the operation.
Advantages for patients include less pain, smaller scars, shorter hospital stays, and faster recovery compared to traditional open surgery. Common laparoscopic procedures include gallbladder removal, appendectomy, and hernia repair. The surgeon controls everything from outside the body, viewing magnified internal images in real-time on screen.
Risks are minimal but include infection, bleeding, and rare organ damage. Most patients go home the same day or after one overnight stay and return to normal activities within 1-2 weeks, compared to 4-6 weeks for open surgery.
Levitra (Vardenafil)
Levitra is an oral medication used to treat erectile dysfunction (difficulty achieving or maintaining erections). It works by relaxing blood vessel muscles in the penis, allowing more blood flow during sexual stimulation, which produces and sustains an erection.
The medication is taken 25-60 minutes before sexual activity and remains effective for 4-5 hours. Results vary by individual; some men notice improvement within 15 minutes, while others need up to an hour. Levitra is available in 5mg, 10mg, and 20mg tablets and is marketed under different brand names including Levitra (Bayer) and Vivanza (GSK).
Common side effects include headache, flushing, and stuffy nose. Do not take Levitra if you use nitrate medications for heart problems or have severe heart or liver disease. It’s important to discuss your medical history and other medications with your doctor before starting treatment. Levitra is similar to Viagra and Cialis but may work better for some patients.
N
Neuromodulation
Neuromodulation is a treatment that uses electrical stimulation or medication to alter nerve activity and reduce pain or improve function. A small device (similar to a pacemaker) is implanted near the spine or nerves, sending mild electrical pulses that interrupt pain signals before they reach the brain.
Neuromodulation is used for chronic pain conditions like back pain, nerve pain, and failed back surgery syndrome when other treatments haven’t worked. The device can be adjusted externally to control pain relief without additional surgery. Benefits include reduced medication use, improved quality of life, and reversibility if the treatment doesn’t work.
Neoplasia
Neoplasia is the medical term for an abnormal growth of tissue, commonly called a tumor. It occurs when cells grow uncontrollably and divide more than normal, forming a mass that differs from healthy surrounding tissue and persists even after the original cause is removed.
Neoplasias can be benign (non-cancerous, not life-threatening) or malignant (cancerous, potentially dangerous). Benign tumors grow slowly, don’t spread, and rarely return after removal. Malignant tumors grow quickly, invade nearby tissues, spread to other parts of the body (metastasis), and can be life-threatening. Diagnosis requires biopsy to determine the tumor type and treatment plan.
O
Orchidopexy
Orchidopexy is a surgical procedure to bring an undescended testicle (cryptorchidism) down into the scrotum where it belongs. During normal development, testicles descend from the abdomen into the scrotum before birth, but sometimes one or both fail to descend.
An undescended testicle increases the risk of infertility, testicular cancer, and tissue damage if left untreated. Surgery is recommended between 6-18 months of age, ideally before age 2, to give the testicle the best chance of normal function. The surgeon makes a small incision, locates the testicle, frees it from surrounding tissue, and secures it in the scrotum with stitches.
Most boys recover quickly with minimal discomfort and resume normal activities within a few weeks. Early treatment before age 1-2 significantly improves fertility and reduces cancer risk. The procedure has a high success rate and is one of the most common pediatric urological surgeries.
P
Papilloma
A papilloma is a benign (non-cancerous) growth that develops on the skin or mucous membranes. Common papillomas appear as warts on the skin, but they can also grow inside the body, particularly in the larynx (voice box) and bladder. Most papillomas are caused by human papillomavirus (HPV) infection and don’t become cancerous, though some types require monitoring or removal if they cause symptoms or obstruct airways/urinary flow.
Pampiniform Plexus
The pampiniform plexus is a network of veins that surround the spermatic cord and drain blood from the testicles. It consists of three groups of veins that work together: the anterior spermatic veins drain into the inferior vena cava (right side) or renal vein (left side), the middle veins accompany the vas deferens into the pelvis, and the posterior veins drain into the epigastric and pudendal veins. Problems with this venous network can cause varicocele (enlarged veins) affecting fertility.
Penis
The penis is the male external reproductive organ that serves two functions: it carries urine from the bladder through the urethra and delivers semen during sexual intercourse. It consists of three columns of erectile tissue (corpora cavernosa and corpus spongiosum) that fill with blood during arousal to produce an erection.
Penectomy
Penectomy is surgical removal of part or all of the penis, usually performed to treat advanced penile cancer. Partial penectomy removes only the affected section and preserves urinary and sexual function when possible. Total penectomy removes the entire organ and requires an alternative method for urination (urinary diversion). The decision depends on tumor size, location, and stage.
Penile Cancer
Penile cancer is a rare malignant tumor of the penis, with about 95% being squamous cell carcinomas (skin cancer). Risk factors include HPV infection, smoking, poor hygiene, and phimosis (tight foreskin). Early symptoms include lumps, discoloration, bleeding, or discharge. Treatment ranges from topical cream or laser for early stages to surgery and chemotherapy for advanced disease. Early detection significantly improves outcomes.
Penile Pearly Papules (PPP)
Penile pearly papules (PPP) are small, benign bumps (1-3 mm) that appear around the crown of the glans (head) of the penis. They’re harmless, don’t cause pain or itching, and affect approximately 10-15% of men, particularly those with darker skin. They’re not contagious, don’t require treatment, and are purely cosmetic. Some men may seek removal for cosmetic reasons using laser or cryotherapy.
Penoscopy (Peniscopy)
Penoscopy is a non-invasive examination technique using magnification and special lighting (sometimes with surface microscopy) to closely evaluate the skin and mucous membranes of the external male genitalia. It’s useful for detecting early signs of infection, inflammation, cancer, or HPV-related changes that aren’t visible to the naked eye. The procedure is quick, painless, and performed by dermatologists or urologists.
Prepuce
The prepuce (foreskin) is loose, retractable skin that covers and protects the glans (head) of the penis. In uncircumcised men, it slides back during erection and pulls forward when soft. The foreskin produces natural lubricating oils and protects the sensitive glans. Phimosis occurs when the foreskin is too tight to retract, and circumcision (surgical removal) is performed if it causes problems.
Prostate
The prostate is a walnut-sized gland that produces seminal fluid, a nutrient-rich liquid that nourishes and transports sperm during ejaculation. Located below the bladder and surrounding the urethra, the prostate can be felt by a doctor during a rectal exam (about 5 cm from the anus). The prostate grows throughout life, which is normal, but enlargement can obstruct urination. It varies significantly in size and function across different mammalian species.
Prolapse
Prolapse is the abnormal descent or protrusion of an organ from its normal position, usually through natural body openings. Rectal prolapse (intestines pushing through the anus) is most common, followed by bladder and uterine prolapse. Symptoms include pain, bleeding, difficulty with bowel/bladder control, and a visible bulge. Treatment depends on severity, ranging from pelvic floor exercises to surgery.
Pyeloureteral Junction
The pyeloureteral junction is where the kidney’s collecting system (renal pelvis) connects to the ureter, the tube that carries urine to the bladder. Narrowing at this junction obstructs urine flow, causing the renal pelvis and kidney chambers (calyces) to dilate and fill with backed-up urine. This pressure damages kidney tissue and can eventually destroy kidney function. Surgery to widen or reconstruct the junction is often necessary to prevent permanent kidney damage.
R
Radiology (Diagnostic Radiology, Radiodiagnostics)
Radiology is the medical specialty that uses X-rays and other imaging techniques to diagnose and treat diseases. Radiologists produce images of the inside of your body using ionizing radiation (X-rays), then interpret these images to identify problems like broken bones, infections, tumors, or organ damage. Modern radiology also includes CT scans, ultrasound, and MRI. Radiation exposure is kept to a minimum through lead protection and careful technique, and the diagnostic benefits usually outweigh the small radiation risk.
Reproduction
Reproduction is the biological process by which living organisms create new individuals of the same species, passing genetic information from parents to offspring. In humans, this involves the union of male sperm and female egg to create an embryo that develops into a baby. Sexual reproduction combines DNA from both parents, creating genetic diversity. Reproduction is essential for species survival and continuation of life.
S
Scrotum
The scrotum is the pouch of skin that hangs between the thighs and contains the testicles, epididymides (sperm-storing structures), and the lower part of the spermatic cord. It’s located below the pubic bone and behind the base of the penis. The scrotum maintains optimal temperature for sperm production by contracting in cold and relaxing in heat.
Semen
Semen is the whitish or milky fluid released during ejaculation that contains sperm and nutrients. It’s produced by the testicles, prostate gland, and seminal vesicles working together. Semen nourishes and transports sperm to the female reproductive tract during intercourse, giving sperm the best chance of fertilizing an egg.
Semen Analysis (Spermiogram)
Semen analysis is a laboratory test that evaluates sperm quality to assess male fertility. The patient abstains from sexual activity for 3-5 days, then provides a semen sample in a sterile container at the lab. The analysis examines sperm count (how many), morphology (shape and size), and motility (movement ability). Results help doctors diagnose fertility problems and guide treatment options like medication or assisted reproduction.
Sildenafil (Viagra)
Viagra is an oral medication that treats erectile dysfunction by increasing blood flow to the penis during sexual stimulation. It works by relaxing blood vessel muscles and is taken 30-60 minutes before sexual activity. Effects last 4-6 hours. Common side effects include headache, flushing, and indigestion. Viagra is not effective without sexual stimulation and should not be taken with nitrate medications used for heart problems.
Sphincter
A sphincter is a circular muscle that surrounds body openings and passages, controlling the flow of substances through them. When it contracts, it tightens and closes the opening; when it relaxes, it opens to allow passage. Examples include the anal sphincter (controls bowel movements) and urethral sphincter (controls urination). Some sphincters work automatically; others can be controlled voluntarily.
Stenosis
Stenosis is abnormal narrowing of a body passage, such as blood vessels, ducts, or hollow organs, that obstructs normal flow of blood, urine, or other substances. Common types include urethral stenosis (narrowed urethra blocking urine flow) and vascular stenosis (narrowed blood vessels). Causes include scar tissue, inflammation, or tumors. Treatment ranges from medication to surgical widening (dilation) or bypass procedures.
Suspensory Ligament
The suspensory ligament is a connective tissue band that attaches the penis to the pubic bone and helps support it during erection. It keeps the penis angled against the pubic bone and maintains its position. Injury or stretching of this ligament can affect penile curvature and erectile function.
Syphilis
Syphilis is a sexually transmitted infection caused by the bacterium Treponema pallidum (a spiral-shaped microorganism). It spreads through sexual contact with an infected person’s sores or can pass from mother to fetus during pregnancy. Early symptoms include painless sores (chancre), then rash, fever, and swollen lymph nodes. Without treatment, syphilis can damage the heart, brain, and organs. Antibiotics (usually penicillin) cure syphilis if caught early, making regular STI screening important for sexually active people.
T
Tadalafil (Cialis)
Cialis is an oral medication that treats erectile dysfunction by increasing blood flow to the penis. Unlike Viagra, Cialis has a much longer effect—up to 36 hours compared to 4-6 hours—making it popular for men who want more spontaneity. It can be taken daily in low doses or as needed before sexual activity. Side effects include headache, indigestion, and back pain. Cialis should not be combined with nitrate heart medications.
Testicle (Testis)
The testicle (testis) is the male reproductive gland that produces sperm and testosterone. A healthy adult male has two testicles located inside the scrotum. They develop during fetal growth and begin producing sperm at puberty. Each testicle is about the size of an olive and contains hundreds of coiled tubes (seminiferous tubules) where sperm are manufactured continuously throughout life.
Testicular Cancer
Testicular cancer develops in one or both testicles and can be either germinal (from sperm-producing cells) or non-germinal (from supporting cells). Germinal tumors include seminomas and non-seminomas. Symptoms include a lump, swelling, or heaviness in the scrotum. Testicular cancer has an excellent prognosis when caught early, with cure rates above 90% even for advanced cases. Treatment includes surgery to remove the testicle, followed by chemotherapy or radiation if needed. Regular self-examination helps with early detection.
Tunica Albuginea
The tunica albuginea is a tough, fibrous sheath made of dense connective tissue, smooth muscle fibers, and elastic fibers that completely surrounds and protects each testicle. This thick layer gives the scrotum its characteristic whitish color and helps maintain testicular structure and function. Diseases affecting this layer, like Peyronie’s disease, can cause serious problems with penile function.
TURP (Transurethral Resection of the Prostate)
TURP is the gold standard surgical treatment for benign prostate enlargement (BPH) that causes severe urination problems. The surgeon inserts a thin instrument through the urethra to carefully remove excess prostate tissue blocking urine flow, without making external incisions. Recovery is quick (1-2 days hospital stay), and 80-90% of patients experience excellent symptom relief. Side effects may include temporary urinary incontinence or retrograde ejaculation (semen entering the bladder). TURP remains the most commonly performed prostate surgery worldwide.
U
Urethra
The urethra is the tube that carries urine from the bladder to the outside of the body. In women, it’s a short tube used only for urination. In men, the urethra is longer and serves double duty—it carries both urine and semen during ejaculation, as the ejaculatory ducts empty into it from the prostate and seminal vesicles.
Ureter
The ureter is a muscular tube that connects each kidney’s collecting system (renal pelvis) to the bladder. You have two ureters, one from each kidney. They transport urine from the kidneys to the bladder through wave-like muscle contractions called peristalsis, working continuously throughout the day and night.
Urinary Bladder
The bladder is a hollow, muscular organ in the pelvis that stores urine produced by the kidneys. It expands as it fills and contracts to empty during urination (micturition). The process involves both voluntary control (you decide when to urinate) through the external sphincter muscle and automatic reflex control through the spinal cord. A normal bladder can hold 400-600 ml of urine.
Urine
Urine is a liquid waste product containing water, urea (nitrogen waste from protein breakdown), and other metabolic byproducts filtered from the blood by the kidneys. It travels from the kidneys through the ureters into the bladder, then exits the body through the urethra during urination. The color, smell, and composition of urine can indicate overall health and kidney function.
Urobilin
Urobilin is a yellow pigment produced from the breakdown of hemoglobin (the protein in red blood cells). It’s what gives urine its characteristic yellow color. Urobilin is also present in bile and contributes to stool color. In the intestines, it acts as a natural detergent. Abnormal urobilin levels in urine can indicate liver or blood disorders.
Uroflowmetry
Uroflowmetry is a simple, non-invasive test that measures the rate and pattern of urine flow. The patient urinates into a special toilet that records maximum flow rate and average flow. Results help doctors detect urethral obstruction or bladder dysfunction. Important note: a normal flow rate doesn’t completely rule out obstruction, so additional tests may be needed for diagnosis.
Urography (IVP)
Urography is a radiological imaging test (often called intravenous pyelography or IVP) that uses X-rays and contrast dye to visualize the entire urinary system—kidneys, ureters, and bladder. The dye is injected intravenously, filtered by the kidneys into urine, and shows up on X-rays, revealing both the structure and function of the urinary tract. It helps diagnose kidney stones, tumors, obstructions, and infections.
Urology
Urology is the medical and surgical specialty that diagnoses and treats diseases of the urinary system (kidneys, ureters, bladder, urethra) and male reproductive system (prostate, testicles, penis, scrotum). Urologists perform both medical management with medications and surgical procedures. They treat conditions ranging from infections and stones to cancer and erectile dysfunction.
V
Varicocele
Varicocele is an enlargement of the veins (varicose veins) in the scrotum that drain blood from the testicles, similar to varicose veins in the legs. The affected veins become dilated and don’t close properly, allowing blood to pool and creating a “bag of worms” appearance. Varicocele affects about 15% of men and is the most common cause of male infertility. It can cause pain, testicular atrophy (shrinkage), and reduced sperm production. Treatment includes surgery to ligate (tie off) or remove the abnormal veins, improving fertility in many cases.
Vasectomy
Vasectomy is a permanent male sterilization procedure that blocks the vas deferens (the tubes carrying sperm from the testicles). The surgeon makes small incisions, locates the vas deferens on each side, cuts or ties them, and seals the ends. This prevents sperm from mixing with semen during ejaculation, so no sperm are present in the ejaculate. The procedure is highly effective (>99%), quick, minimally invasive, and performed under local anesthesia as an outpatient procedure. Reversal is possible but not always successful.
Virus
A virus is a microscopic infectious agent that exists as a parasite, meaning it can only reproduce inside host cells. Viruses are much smaller than bacteria and contain genetic material (DNA or RNA) surrounded by a protein coat. They cause infection by entering cells, hijacking the cell’s machinery to make copies of themselves, and then bursting out to infect more cells. Common viral infections include colds, flu, HPV, and herpes.
Reception and Assistance
Prof. Antonini works at the following healthcare facilities:
Quisisana
Via Gian Giacomo Porro, 5 – 00197 Rome - Italy
Telephone +39 06 809581
Santa Lucia
Via Ospedale, 2 – 06034 Foligno (PG)- Italy
Telephone +39 0742 710080
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Via Fontana, 2 – 20122 Milan – Italy
Telephone +39 02 7631 6689
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C. de la Granja, 8, Chamberí – 28003 Madrid, Spain
Telephone +34 622 28 44 25
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(+39) 351 7844455
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